Dieses Projekt wird zum Teil im Rahmen der Klinischen Forschergruppe 117 bearbeitet.

 

  

Projektrelevante Publikationen:

 

Pizanis N, Petrov A, Heckmann J, Wiswedel I, Wohlschläger J, de Groot H, Jakob H, Rauen U, Kamler M.
A new preservation solution for lung transplantation. Evaluation in a porcine transplantation model.
J Heart Lung Transplant 31, 310-7 (2012)

Türk TR, Su S, Rauen U, Feldkamp T, de Groot H, Kribben A, Witzke O.
Reduction of chronic graft injury with a new HTK-based preservation solution in a murine heart transplantation model.
Cryobiology 64, 273-8 (2012)

Liu Q, Bruns H, Schultze D, Xue Y, Zorn M, Flechtenmacher C, Straub BK, Rauen U, Schemmer P.
HTK-N, a modified HTK solution, decreases preservation injury in a model of microsteatotic rat liver transplantation.
Langenbecks Arch Surg 397, 1323-31 (2012)

Fingas CD, Wu S, Gu Y, Wohlschlaeger J, Scherag A, Dahmen U, Paul A, de Groot H, Rauen U.
Assessment of a chloride-poor vs. a chloride-containing modified HTK solution in a rat liver transplantation model.
Liver Transplantation 17, 650-660 (2011) 

Benko T, Frede S, Gu Y, Best J, Baba HA, Schlaak JF, de Groot H, Fandrey J, Rauen U.
Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.
J Invest Surg 23, 12-20 (2010)

de Groot H, Rauen U.
Ischemia-reperfusion injury: processes in pathogenetic networks: a review.
Transplant Proc 39, 481-484 (2007)

Rauen U, de Groot H.
Apoptose bei kalter Ischämie und warmer Reperfusion.
TransplantLinc 1-2004, 46-56 (2004)

Rauen U, de Groot H.
New insights into the cellular and molecular mechanisms of cold storage injury.
J Investig Med 52, 299-309 (2004)

Bartels-Stringer M, Kramers C, Wetzels JFM, Russel FGM, de Groot H, Rauen U.
Hypothermia causes a marked injury to rat proximal tubular cells that is aggravated by all currently used preservation solutions. Cryobiology 47, 82-91 (2003)

Rauen U, de Groot H.
Mammalian cell injury induced by hypothermia – the emerging role for reactive oxygen species.
Biol Chem 383, 477-488 (2002)

Frank A, Rauen U, de Groot H.
Protection by glycine against hypoxic injury of rat hepatocytes: inhibition of ion fluxes through nonspecific leaks.
J Hepatol 32, 58-66 (2000)

Fuckert O, Rauen U, de Groot H.
A role for sodium in hypoxic but not in hypothermic injury to hepatocytes and LLC-PK₁ cells.
Transplantation 70, 723-730 (2000)